In some couples, no clear medical reason is found even after evaluation.

What Is Unexplained Infertility?   Unexplained infertility is diagnosed when a couple cannot conceive despite regular unprotected intercourse and all standard fertility tests (ovulation, sperm quality, hormone levels, fallopian tubes) appear normal. It affects about 10–15% of couples experiencing infertility.   ⸻   2️⃣ Possible Hidden Causes   Although routine tests show no problem, some …

What Is Unexplained Infertility?
 
Unexplained infertility is diagnosed when a couple cannot conceive despite regular unprotected intercourse and all standard fertility tests (ovulation, sperm quality, hormone levels, fallopian tubes) appear normal.
It affects about 10–15% of couples experiencing infertility.
 
 
2️⃣ Possible Hidden Causes
 
Although routine tests show no problem, some subtle factors may be involved:
•Poor egg or sperm quality not detected by standard tests.
•Minor hormonal imbalances affecting timing of ovulation.
•Issues with the fertilization process or early embryo development.
•Problems with implantation or immune system reactions.
•Psychological stress or chronic inflammation.
 
 
3️⃣ Diagnosis and Approach
 
Since there is no clear cause, the focus is on comprehensive testing and observation:
•Tracking ovulation and luteal phase hormones.
•Advanced sperm DNA testing.
•Uterine and endometrial assessment.
•Lifestyle and stress evaluation.
 
 
4️⃣ Treatment Options
•Timed intercourse or ovulation induction: To improve timing and ovulation quality.
•IUI (Intrauterine Insemination): Increases the chances of sperm meeting the egg.
•IVF (In Vitro Fertilization): Often recommended after unsuccessful cycles.
•ICSI: Helps when subtle sperm issues are suspected.
•Lifestyle optimization: Balanced nutrition, stress reduction, and maintaining a healthy weight.
 
 
5️⃣ Prognosis
 
Even though the cause is unclear, the success rate for pregnancy is high with proper management.
Many couples eventually conceive naturally or through assisted reproductive techniques.

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